Esslingen is located in the Neckar Valley near Stuttgart. Behind it the Neckar becomes unnavigable upstream, and from Stuttgart to Esslingen endless factories, plants and power plants stretch along the river.
Therefore, despite the fact that the old city itself is pretty, you can easily replace it with another one. You can find the same well-preserved half-timbered house in less industrial places: in Tübingen, Bad Wimpfen, Besigheim, not to mention the Black Forest.